Fibrinolysis

Fibrinolysis is a process that prevents blood clots from growing and becoming problematic.[1] Primary fibrinolysis is a normal body process, while secondary fibrinolysis is the breakdown of clots due to a medicine, a medical disorder, or some other cause.[2]

In fibrinolysis, a fibrin clot, the product of coagulation, is broken down.[3] Its main enzyme plasmin cuts the fibrin mesh at various places, leading to the production of circulating fragments that are cleared by other proteases or by the kidney and liver.

  1. ^ Mckenzie, Samuel (2019-03-27). "What is Fibrinolysis?". News-Medical. Retrieved 2024-05-31.
  2. ^ Dugdale D. "Fibrinolysis - primary or secondary". MedlinePlus. Retrieved August 7, 2011.
  3. ^ Cesarman-Maus G, Hajjar KA (May 2005). "Molecular mechanisms of fibrinolysis". British Journal of Haematology. 129 (3): 307–21. doi:10.1111/j.1365-2141.2005.05444.x. PMID 15842654.
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