Fox–Fordyce disease

Fox–Fordyce disease
Other namesApocrine miliaria
SpecialtyDermatology 

Fox–Fordyce disease (FFD) is a chronic blockage of the sweat gland ducts with a secondary, non-bacterial inflammatory response to the secretions and cellular debris in the cysts.[1] The inflammation is often accompanied by intense itching.[2] In general, the disease often causes skin to darken near the affected area and raised bumps or papules to appear.[3] In addition, hair follicles can become damaged which cause hair loss.[3] Hidradenitis is very similar, but tends to have a secondary bacterial infection so that pus-draining sinuses are formed. It is a very devastating skin disease that does not have universally curative treatments.

  1. ^ Freedberg, et al. (2003). Fitzpatrick's Dermatology in General Medicine. (6th ed.). McGraw-Hill. p. 709. ISBN 0-07-138076-0.
  2. ^ "Fox Fordyce Disease - Symptoms, Causes, Treatment | NORD". rarediseases.org. Retrieved 28 April 2023.
  3. ^ a b Meehan, Shane A.; Robinson, Maria; Yost, John (December 2012). "Fox-Fordyce disease". Dermatology Online Journal. 18 (12).
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