Interleukin 9

IL9
Identifiers
Aliases	IL9, HP40, IL-9, P40, interleukin 9
External IDs	OMIM: 146931; MGI: 96563; HomoloGene: 492; GeneCards: IL9; OMA:IL9 - orthologs
Gene location (Human)
Chr.	Chromosome 5 (human)
End	135,895,841 bp
Gene location (Mouse)
Chr.	Chromosome 13 (mouse)
End	56,630,059 bp
RNA expression pattern
	Top expressed in
	tibial nerve; ; sural nerve; ; amygdala; ; caudate nucleus; ; Brodmann area 9; ; right frontal lobe; ; substantia nigra; ; primary visual cortex; ; putamen; ; cingulate gyrus;
	Top expressed in
	embryo; ; entorhinal cortex; ; CA3 field; ; choroid plexus of fourth ventricle; ; zygote; ; inferior colliculi; ; spermatocyte; ; uterus; ; gonad; ; male reproductive system;
	More reference expression data
	More reference expression data
Gene ontology
Molecular function	interleukin-9 receptor binding; cytokine activity; growth factor activity; cytokine receptor binding;
Cellular component	extracellular region; extracellular space;
Biological process	positive regulation of cell growth; inflammatory response; immune response; positive regulation of cell population proliferation; regulation of signaling receptor activity; interleukin-9-mediated signaling pathway;
	Sources:Amigo / QuickGO
Orthologs
	3578
	16198
	ENSG00000145839
	ENSMUSG00000021538
	P15248
	P15247
	NM_000590
	NM_008373
	NP_000581
	NP_032399
	Wikidata
View/Edit Human	View/Edit Mouse

Interleukin 9, also known as IL-9, is a pleiotropic cytokine (cell signalling molecule) belonging to the group of interleukins.^[5] IL-9 is produced by variety of cells like mast cells, NKT cells, Th2, Th17, Treg, ILC2, and Th9 cells in different amounts. Among them, Th9 cells are regarded as the major CD4+ T cells that produce IL-9.^[6]

^ ^a ^b ^c GRCh38: Ensembl release 89: ENSG00000145839 – Ensembl, May 2017
^ ^a ^b ^c GRCm38: Ensembl release 89: ENSMUSG00000021538 – Ensembl, May 2017
^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ "Entrez Gene: IL9 interleukin 9".
^ Rojas-Zuleta WG, Sanchez E (2017). "IL-9: Function, Sources, and Detection". Th9 Cells. Methods in Molecular Biology. Vol. 1585. pp. 21–35. doi:10.1007/978-1-4939-6877-0_2. hdl:10161/14730. ISBN 978-1-4939-6876-3. PMID 28477184.

[refGRCh38Ensembl-1] GRCh38: Ensembl release 89: ENSG00000145839 – Ensembl, May 2017

[refGRCm38Ensembl-2] GRCm38: Ensembl release 89: ENSMUSG00000021538 – Ensembl, May 2017

[3] "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[4] "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[entrez-5] "Entrez Gene: IL9 interleukin 9".

[RojasZuleta_2017-6] Rojas-Zuleta WG, Sanchez E (2017). "IL-9: Function, Sources, and Detection". Th9 Cells. Methods in Molecular Biology. Vol. 1585. pp. 21–35. doi:10.1007/978-1-4939-6877-0_2. hdl:10161/14730. ISBN 978-1-4939-6876-3. PMID 28477184.

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