Pseudoephedrine/loratadine

Pseudoephedrine/loratadine
Combination of
PseudoephedrineSympathomimetic
LoratadineH1 antagonist
Clinical data
Trade namesClaritin-D, others
AHFS/Drugs.comclaritin-d
Routes of
administration		By mouth
ATC code
Legal status
Legal status
Identifiers
CAS Number
  (verify)

Pseudoephedrine/loratadine, sold under the brand name Claritin-D among others, is an orally administered combination medication used for the treatment of allergic rhinitis (hay fever) and the common cold.[1] Pseudoephedrine, one of the naturally occurring alkaloids of ephedra, is a sympathomimetic used as a decongestant. It produces a decongestant effect that is facilitated by the vasoconstriction in the mucosal capillaries of the upper respiratory areas. Loratadine is a long-acting antihistamine (H1 histamine antagonist) that is less sedating than older substances of its type.

In 2022, it was the 289th most commonly prescribed medication in the United States, with more than 500,000 prescriptions.[2][3]

  1. ^ a b "Claritin-D 12 hour- loratadine and pseudoephedrine sulfate tablet, extended release". DailyMed. 30 November 2023. Retrieved 8 July 2024.
  2. ^ "The Top 300 of 2022". ClinCalc. Archived from the original on 30 August 2024. Retrieved 30 August 2024.
  3. ^ "Loratadine; Pseudoephedrine Drug Usage Statistics, United States, 2013 - 2022". ClinCalc. Retrieved 30 August 2024.
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